Bcl x (BCL2L1) pThr115 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: The antibody, when 1:10,000 1:100,000 diluted, can detect the Threonine 115 phosphorylated Bcl-xL coated on ELISA plate.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide derived from Threonine 115 phosphorylated Bcl-xL, conjugated with KLH
Specificity	This antibody detects Human and other species with consensus Bcl-xL peptide (TSQLHITpPGTAY).
Formulation	0.01M PBS, pH 7.4 State: Azide Free State: Lyophilized Ig fraction
Purification	Protein G affinity
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	BCL2 like 1
Database Link	Entrez Gene 598 Human UniProt ID Q07817
Background	Bcl-xL is a prosurvival factor in the Bcl-2 family. It is a mitochondrial outer membrane protein that regulates the voltage-dependent anion channels (VDAC), and controls the production of reactive oxygen species and the release of cytochrome C. Bcl-xL gene knock-out resulted in embryonic lethality in animal model due to neuronal apoptosis and erythroid apoptosis. Bcl-xL is believed to be involved with the survival and differentiation of erythroid cells, iron metabolism and hemoglobin synthesis.
Synonyms	Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
Reference Data

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