C3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Frozen Sections: The typical starting working dilution is 1/10. Western blot: The typical starting working dilution is 1/10. The antibody works well in both PBS and in TBS.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody detects Mouse complement factor C3. Other species not tested.
Formulation	PBS State: Purified State: Liquid Ig fraction Stabilizer: 0.1% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Gene Name	complement component 3
Database Link	Entrez Gene 12266 Mouse UniProt ID P01027
Background	The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
Synonyms	CPAMD1, Complement component 3
Reference Data

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