cyclic GMP Rabbit Polyclonal Antibody

CAT#: AP23444SU-N

cyclic GMP rabbit polyclonal antibody, Serum

Size: 20 ul 100 ul



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CNY 7,161.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Applications R
Recommend Dilution RIA
Antigen binding capacity: Dilutions 1/2000 bound 45-50% of the labelled (radioactive) nucleotide.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Succinyl cGMP- Human Serum Albumin conjugate
Specificity Cross-reactivity at 50% displacement:
cAMP < 0.0005%
GTP < 0.00001%
ATP < 0.00001%
Formulation State: Serum
State: Lyophilized Serum
Reconstitution Method Restore in aqua bidest to initial volume.
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Background Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Synonyms cGMP, cyclic guanosine monophosphate
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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