Col7a1 (NC1 FN-III-like Dom 7+8) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC
Recommend Dilution	ELISA. Immunofluorescence. Immunohistochemistry on Cryosections (Ref.3) Induction of Experiemental EBA in Mice (Ref.2,3).
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Murine Collagen type VII (aa 757-967) GST fusion protein.
Specificity	This antibody recognizes Murine 290 kDa type VII Collagen (epidermal basement membrane / anchoring fibril component).
Formulation	PBS, pH 7.2 State: Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore in aqua bidest to 1 mg/ml.
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	collagen, type VII, alpha 1
Database Link	Entrez Gene 12836 Mouse UniProt ID Q63870
Background	Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.
Synonyms	COL7A1, Long-chain collagen, LC collagen
Reference Data

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