GST3 (GSTP1) (C-term) Rabbit Polyclonal Antibody
CAT#: AP23405PU-N
GST3 (GSTP1) (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 5,599.00
货期*
5周
规格
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | Western blot: At 1-2μg/ml with the appropriate system to detect GSTpi in cells and tissues. Immunohistochemistry on paraffin sections: At 1-2μg/ml to detect GSTpi in formalin fixed and paraffin embedded tissues. Boiling the sections is required. Immunocytochemistry: At 0.5-1μg/ml to detect GSTpi in acetone fixed cell. Antigen retrieval by Pepsin and Trypsin is required. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A peptide mapping at the C-terminus of GSTpi of human origin |
Formulation | State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | 1.2% sodium acetate or neutral PBS. If 0.5ml of PBS is used, the antibody concentration will be 100μg/ml. |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Gene Name | glutathione S-transferase pi 1 |
Database Link | |
Background | Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound. |
Synonyms | Glutathione S-transferase P, GSTP1-1, GST pi, GST class-pi, FAEES3 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer |
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