Cytochrome C (CYCS) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: At 0.1-0.5 μg/ml with the appropriate system to detect Cytochrome C in cells and tissues. Immunohistochemistry on Paraffin Sections: At 0.5-1 μg/ml to detect Cytochrome C in formalin fixed and paraffin embedded tissues. Immunohistochemistry on Frozen Sections: At 0.5-1 μg/ml to detect Cytochrome C in formalin or acetone fixed tissues.  Immunocytochmeistry: 1 µg/ml.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence at the C-terminal of human Cytochrome C
Specificity	This antibody detects Cytochrome c (C-term, 91-105). No cross reactivity with other proteins.
Formulation	0.9mg NaCl, 0.2mg Na2HPO4 State: Aff - Purified State: Lyophilized Ig fraction Stabilizer: 5mg BSA Preservative: 0.05mg Thimerosal, 0.05mg Sodium Azide
Reconstitution Method	0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cytochrome c, somatic
Database Link	Entrez Gene 13063 MouseEntrez Gene 25309 RatEntrez Gene 54205 Human UniProt ID P99999
Background	Cytochrome C is located in the mitochondria of all aerobic cells and is involved in the electron transport system. Human cytochrome c has 104 amino acid residues and a molecular weight of 11,458 and is mapped to 7p15.2. Cytochrome c released from mitochondria has been proposed to be an essential component of an apoptotic pathway responsive to DNA damage and other forms of cell stress. And it has a role in different apoptotic signaling cascades.
Synonyms	CYCS, CYC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Small cell lung cancer, Viral myocarditis

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