Aquaporin 1 (AQP1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: At 0.1-0.5 μg/ml with the appropriate system to detect AQP1 in cells and tissues. Immunohistochemistry on paraffin sections: At 0.5-1.0 μg/ml to detect AQP1 in formalin fixed and paraffin embedded tissues.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence mapping near the C-terminal of human AQP1
Specificity	This antibody detects Aquaporin-1 (C-term). No cross reactivity with other proteins.
Formulation	5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	0.2ml of distilled water will yield a concentration of 500μg/ml.
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	aquaporin 1 (Colton blood group)
Database Link	Entrez Gene 11826 MouseEntrez Gene 25240 RatEntrez Gene 358 Human UniProt ID P29972
Background	Aquaporin 1 is a 28-kD integral protein thought at first to be a breakdown product of the Rh polypeptide but was later shown to be a unique molecule that is abundant in erythrocytes and renal tubules.AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Synonyms	AQP-1, CHIP28, Aquaporin-CHIP
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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