Neurotrophin 3 (NTF3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: Use at 1-2 μg/ml with the appropriate system to detect NT-3 in cells and tissues. Immunohistochemistry on Paraffin Sections: Use at 0.5-1 μg/ml to detect NT-3in formalin fixed and paraffin embedded tissues.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide mapping at the middle region of Human Neurotrophin-3
Specificity	This antibody detects Neurotrophin 3 / NTF3 in the middle.
Formulation	50% Glycerol, 0.9mg NaCl, 0.2mg Na2HPO4 State: Aff - Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% Sodium Acetate or neutral PBS.
Concentration	0.1 mg/ml (after reconstitution with 0.5 ml PBS)
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for 3 months or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	neurotrophin 3
Database Link	Entrez Gene 18205 MouseEntrez Gene 81737 RatEntrez Gene 4908 Human UniProt ID P20783
Background	Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.
Synonyms	Neurotrophin-3, NT-3, Neurotrophic factor, HDNF, Nerve growth factor 2, NGF-2
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	MAPK signaling pathway, Neurotrophin signaling pathway

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