DDX58 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from human DDX58 / RIG-1 / RIG-I
Specificity	This antibody reacts to RNA Helicase (RIG-I) (DDX58).
Formulation	Tris saline, 0.02% Sodium Azide, pH 7.3, 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity purified
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	DEXD/H-box helicase 58
Database Link	Entrez Gene 23586 Human UniProt ID O95786
Background	EAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
Synonyms	RIG-1, RIG-I, DKFZp434J1111, DKFZp686N19181, FLJ13599, DEAD box protein 58
Reference Data
Protein Pathways	Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

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