Clusterin (CLU) (488-501) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 1/32000, 0.3 - 1 µg/ml.
Reactivity	Canine, Human, Monkey
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from the C-terminus of human CLU/Clusterin (NP_001822.2; NP_976084.1).
Specificity	This antibody detects Apolipoprotein J (Apo J) at C-term.
Formulation	Tris saline buffer, pH~7.3, 0.5% BSA, 0.02% Sodium Azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	clusterin
Database Link	Entrez Gene 1191 Human UniProt ID P10909
Background	Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself.
Synonyms	Clusterin, APOJ, CLI, KUB1, AAG4, NA1/NA2, SP-40,40
Reference Data
Protein Families	Druggable Genome, Secreted Protein

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.