MCSF Receptor (CSF1R) (734-744) Goat Polyclonal Antibody
CAT#: AP22414PU-N
MCSF Receptor (CSF1R) (734-744) goat polyclonal antibody, Aff - Purified
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CNY 5,371.00
货期*
4周
规格
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | Peptide ELISA: Limit Dlution: 1/8000. Western blot: 0.2-1 µg/ml. In transfected HEK293 transiently expressing full-length Human CSF1R (myc and DYKDDDDK tagged), a band of approx. 200kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody. |
Reactivity | Canine, Human, Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence from the internal region of the protein sequence according to NP_005202.2. |
Specificity | Recognizes CD115/CSF1R (734-744). |
Formulation | Tris saline, pH~7.3 with 0.02% Sodium Azide and 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | colony stimulating factor 1 receptor |
Database Link | |
Background | CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. |
Synonyms | CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor |
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