Desmocollin 1 (DSC1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/1000. IHC: 1:50-100 Flow Cytometry: 1:10-50
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from 659-687 aa of the C-terminal region of human DSC1
Specificity	This antibody reacts to DSC1.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	99987 Da.
Gene Name	desmocollin 1
Database Link	Entrez Gene 1823 Human UniProt ID Q08554
Background	DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.
Synonyms	DG2/DG3, DSC1, CDHF1
Reference Data
Protein Families	Transmembrane

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