Folylpolyglutamate synthase (FPGS) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:100 - 1:500. ELISA: 1:1,000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from the Center region of human FPGS
Specificity	This antibody detects FPGS at Center.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Purified through a protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	folylpolyglutamate synthase
Database Link	Entrez Gene 2356 Human UniProt ID Q05932
Background	FPGS is the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives.
Synonyms	Folylpolyglutamate synthase, Tetrahydrofolate synthase
Note	Molecular weight: 64609 Da
Reference Data
Protein Pathways	Folate biosynthesis, Metabolic pathways

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