Biglycan (BGN) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1/50 - 1/100. ELISA: 1/1,000. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 155~184 amino acids selected from the Center region of human BGN
Specificity	This antibody detects Biglycan at Center.
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	biglycan
Database Link	Entrez Gene 633 Human UniProt ID P21810
Background	BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival.
Synonyms	Bone/cartilage proteoglycan I, PG-S1, PGS1, BGN, SLRR1A
Note	Molecular weight: 41654 Da
Reference Data
Protein Families	Secreted Protein

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