PLK3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP14971PU-N

PLK3 (C-term) rabbit polyclonal antibody, Purified



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CNY 6,314.00


货期*
5周

规格
    • 400 ul

Product images

Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Flow cytometry.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PLK3.
Specificity This antibody reacts to PLK3.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name polo like kinase 3
Background CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.
Synonyms Polo-like kinase 3, CNK, FNK, PRK
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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