B Raf (BRAF) pThr400 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	ELISA: 1/1,000. Dot Blot: 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.
Specificity	This antibody detects B-Raf proto-oncogene (BRAF) pThr400. Predicted to cross react with Mouse (100% Antigen Homology).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	B-Raf proto-oncogene, serine/threonine kinase
Database Link	Entrez Gene 673 Human UniProt ID P15056
Background	BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Synonyms	BRAF, BRAF1, RAFB1, p94
Note	Molecular weight: 84437 Da
Reference Data

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