B Raf (BRAF) pThr598 Rabbit Polyclonal Antibody
CAT#: AP12828PU-N
B Raf (BRAF) pThr598 rabbit polyclonal antibody, Aff - Purified
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CNY 6,314.00
货期*
5周
规格
Specifications
Product Data | |
Recommend Dilution | ELISA: 1/1,000. Dot Blot: 1/100-1/500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T598 of human BRAF. |
Specificity | This antibody detects BRAF pThr598. Predicted to cross react with Mouse (100% Antigen Homology). |
Formulation | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | B-Raf proto-oncogene, serine/threonine kinase |
Database Link | |
Background | BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer. |
Synonyms | BRAF, BRAF1, RAFB1, p94 |
Note | Molecular weight: 84437 Da |
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