IDO1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Peptide ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistchemistry: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO.
Specificity	This antibody detects INDO (C-term).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	indoleamine 2,3-dioxygenase 1
Database Link	Entrez Gene 3620 Human UniProt ID P14902
Background	Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.
Synonyms	IDO1, IDO, INDO, Indoleamine 2,3-dioxygenase 1, EC=1.13.11.52, Indoleamine 2,3-dioxygenase, IDO, Indoleamine-pyrrole 2,3-dioxygenase
Note	Calculated Molecular weight: 45326 Da
Reference Data

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