VIP Receptor 1 (VIPR1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections.
Reactivity	Bovine, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from an internal domain of human VIP-R1 protein
Specificity	Reacts with Human 51 kDa VIP-R1 protein. Cross reacts with Bovine protein
Formulation	State: Purified State: Lyophilized antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	vasoactive intestinal peptide receptor 1
Database Link	Entrez Gene 7433 Human UniProt ID P32241
Background	Vasoactive Intestinal Polypeptide Receptor 1 (VIPR1) is a member of the Vasoactive Intestinal Polypeptide subfamily. Vasoactive intestinal peptide (VIP) plays multiple roles in the nervous, endocrine, and immune systems as a neurotransmitter, a hormone, and a cytokine. VIPR1, a receptor for VIP, has been shown to expressed widely in normal tissues and is the predominant receptor subtype for VIP in cancers. VIP and its receptors, VIPR1 and VIPR2, are highly expressed in the immune system and modulate diverse T cell functions. Recently VIP-R1 has been shown to be a novel and potent facilitator of HIV-1 infection. Two isoforms are produced by alternative splicing.NVIPR1 expression has been documented widely in normal and cancerous tissues, including adipose, adrenal, bladder, blood, brain, breast, colon, ganglion, GI tract, heart, kidney, liver, lung, lymph node, ovary, pancreas, placenta, prostate, skin, small intestine, spinal cord, spleen, stomach, testis, thymus, thyroid, and vessel. ESTs have been isolated from a diverse set of normal and cancerous tissues.
Synonyms	Vasoactive intestinal polypeptide receptor 1, VIPR1, PACAPR2, PACAP-R-2, VIP-R1, VIPR-1
Reference Data

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