CFTR Rabbit Polyclonal Antibody

CAT#: AP10443PU-N

CFTR rabbit polyclonal antibody, Purified



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CNY 6,886.00


货期*
8周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications ELISA, IF, IP, WB
Recommend Dilution ELISA: 1/2000-1/32000.
Western Blot: 1/500-1/1000.
Immunofluorescence.
Immunoprecipitation.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide derived from Cter domain of human CFTR protein.
Specificity Reacts with Human 168 kDa CFTR.
Formulation 0.1M Tris 0.1M Glycine, 2% Sucrose
State: Purified
State: Lyophilized purified antibody
Preservative: None
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name cystic fibrosis transmembrane conductance regulator
Background Cystic Fibrosis (CF) is a common lethal genetic disease characterized by chronic bronchopulmonary disease, elevated sweat electrolytes and insufficient pancreatic function. CF is caused by mutations of the CFTR gene, which encodes the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR protein is a cAMP-activated chloride channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. Approximately 70% of all CF cases share the deletion of a phenylalanine at position 508 which results in abnormal chloride transport. CFTR is structurally similar to multi-drug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
Synonyms Cystic fibrosis transmembrane conductance regulator
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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