17-alpha-Hydroxyprogesterone / 17-OHP Sheep Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: 0.31μg/ml.
Host	Sheep
Clonality	Polyclonal
Immunogen	17-alpha-OH-Progesterone-BTG
Specificity	Determined by biochip immunoassay and expressed as % cross-reactivity. 17α-OH-progesterone 100% The antibody did not cross-react with the following compounds*: Androstenedione Corticosterone Cortisol Deoxycorticosterone Dihydrotestosterone Estradiol Estrone Pregnelone 17-OH Pregnelone Progesterone 11α-OH-progesterone Testosterone *Cross-reactivity profile may vary with tracer used.
Formulation	20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09% Sodium Azide as preservative State: Ig Fraction State: Liquid Ig fraction prepared by Caprylic Acid and Ammonium Sulphate precipitation procedures
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Background	17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, or from 17-hydroxypregnenolone via 3-beta-hydroxysteroid dehydrogenase / Delta 5-4 isomerase. 17-Hydroxyprogesterone is a natural progestogen, and in pregnancy increases in the third trimester primarily due to fetal adrenal production. This hormone is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Hydroxyprogesterone has been used for recurrent miscarriage and various menstrual disorders. Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that hydroxyprogesterone may reduce the risk of preterm delivery.
Synonyms	17OHP, 17-Hydroxyprogesterone, 17-alpha-Hydroxy-Progesterone
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.