Tyrosine Hydroxylase (TH) pSer40 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	Immunofluorescence: 1/100 - 1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 40(R-Q-SP-L-I)
Specificity	Tyrosine Hydroxylase (Phospho-Ser40) Antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 40.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	tyrosine hydroxylase
Database Link	Entrez Gene 21823 MouseEntrez Gene 25085 RatEntrez Gene 7054 Human UniProt ID P07101
Background	Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease
Synonyms	Tyrosine 3-hydroxylase, TYH
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Parkinson's disease, Tyrosine metabolism

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