Acetylcholinesterase (ACHE) (N-term) Rabbit Polyclonal Antibody

CAT#: AP08301PU-N

Acetylcholinesterase (ACHE) (N-term) rabbit polyclonal antibody, Aff - Purified



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CNY 5,654.00


货期*
6周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Immunohistochemistry on Paraffin Sections: 20 µg/ml.
Western Blot: 1 µg/ml.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to N-terminal residues of Human Acetylcholinesterase (N-terminal extended acetylcholinesterase).
Specificity This antibody recognizes Acetylcholinesterase (ACHE).
Formulation PBS containing 0.01% Sodium Azide as preservative and 50% Glycerol as stabilizer.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Immunoaffinity Chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name acetylcholinesterase (Cartwright blood group)
Background Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Synonyms AChE, Acetylcholine Esterase, Acetylcholine-Esterase
Note Predicted Molecular Weight: 68 kDa.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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