Myelin Basic Protein (MBP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 using streptavidin~biotin system or polymer system. Immunofluorescence. Recommended positive control: Human brain.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified human MBP.
Specificity	This antibody stains white matter and oligodendrocyte. Cellular Localization: Cytoplasmic.
Formulation	PBS, pH 7.4 containing 0.05% Sodium Azide as preservative and 1% BSA as stabilizer. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	myelin basic protein
Database Link	Entrez Gene 4155 Human UniProt ID P02686
Background	Myelin Basic Protein (MBP) a 19.6 kDa highly basic protein is a major constituent of central nervous system (CNS). This protein is synthesized by oligodendrocyte and Schwann cells. MBP, Proteolipid (PLP), myelin oligodendrocyte glycoprotein (MOG) are primary encephaltogenic target antigens in multiple sclerosis. The gene for MBP is on chromosome 18; the protein localizes to CNS and to various cells of the hematopoietic system. MBP is expressed in oligodendrocyte, myelin of white matter, spinal cord and in peripheral nerves
Synonyms	MBP
Reference Data

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