Prostate Specific Antigen (KLK3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears). For IHC dilute concentared antibody at 1/50-1/100 using streptavidin~biotin system or polymer system. Immunofluorescence. Recommended Positive Control: Human normal or malignant prostate tissue.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified human PSA.
Specificity	This antibody reacts with prostate ductal epithelium in both normal and malignant prostate tissue. Cellular Localization: Cytoplasmic.
Formulation	PBS, pH 7.4 containing 1% BSA as stabilizer and 0.05% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	kallikrein related peptidase 3
Database Link	Entrez Gene 354 Human UniProt ID P07288
Background	Prostate specific antigen (PSA) is a protein produced by the cells of the prostate gland. PSA is present in small quantities in the serum of normal men, and is often elevated in the presence of prostate cancer and in other prostate disorders. A blood test to measure PSA is the most effective test currently available for the early detection of prostate cancer. Higher than normal levels of PSA are associated with both localized and metastatic prostate cancer Prostate specific antigen (PSA), also known as is a 34 kDa glycoprotein manufactured almost exclusively by the prostate gland. Biochemically it is a serine protease enzyme (kallikrenin family), the gene of which is located on the nineteenth chromosome (19q13).
Synonyms	Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Reference Data

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