Precerebellin (CBLN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 2 - 4 µg/ml.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to 15 amino acid peptide from the middle of Human Precerebellin.
Specificity	15 amino acid peptide from the middle of Human Precerebellin.
Formulation	PBS, containing 0.02% Sodium Azide as preservative. State: Aff - Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Immunoaffinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing.
Gene Name	cerebellin 1 precursor
Database Link	Entrez Gene 869 Human UniProt ID P23435
Background	CBLN1 is required for synapse integrity and synaptic plasticity. It is required for the ER export and secretion of CBLN3. CBLN1 exerts neuromodulatory functions. It directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release.
Synonyms	CBLN1, Precerebellin
Reference Data

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