TIP120B (CAND2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, IP, WB
Recommend Dilution	ELISA: 1/2000 - 1/10000. Immunohistochemistry on Paraffin Sections: 1/500. Immunoprecipitation. Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide
Specificity	This antibody reacts to amino acids 1130-1143 of CAND2/TIP120B (C-terminal) coupled to KLH.
Formulation	State: Liquid purified Ig containing 0.01% (w/v) sodium azide
Concentration	lot specific
Purification	Delipidation and defibrination
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	cullin associated and neddylation dissociated 2 (putative)
Database Link	Entrez Gene 23066 Human UniProt ID O75155
Background	CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B. While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue. This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60% identical in amino acid sequence to TIP120A.
Synonyms	p120 CAND2, KIAA0667, TIP120B
Reference Data

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