Oxytocin Receptor (OXTR) (C-term Cytopl. Dom.) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 40 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human Oxytocin Receptor
Specificity	This antibody detects Oxytocin Receptor (OXTR), C-terminal cytoplasmic domain.
Formulation	Phosphate buffered saline containing 0.09% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	oxytocin receptor
Database Link	Entrez Gene 5021 Human UniProt ID P30559
Background	The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.
Synonyms	OT-R
Reference Data

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