Oligodendrocyte Specific Protein (CLDN11) Rabbit Polyclonal Antibody
CAT#: AP06062PU-N
Oligodendrocyte Specific Protein (CLDN11) rabbit polyclonal antibody, Aff - Purified
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CNY 4,640.00
货期*
2周
规格
Cited in 2 publications. |
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | Western blot: 1/500-1/1000. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-11. |
Specificity | This antibody detects endogenous levels of Claudin 11 protein. (region surrounding Ser198) |
Formulation | Phosphate buffered saline (PBS), pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 0.05% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | ~ 24 kDa |
Gene Name | claudin 11 |
Database Link | |
Background | The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. |
Synonyms | OSP, OTM |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
Complexity and developmental changes in the expression pattern of claudins at the blood–CSF barrier
,null,
Histochemistry and Cell Biology
,PubMed ID 22886143
[CLDN11]
|
Identification of claudins by western blot and immunofluorescence in different cell lines and tissues
,Gonzalez-Mariscal L, Garay E, Quirss M,
Methods Mol. Biol.
,PubMed ID 21717359
[CLDN11]
|
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