IL-1B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FN, WB
Recommend Dilution	ELISA: 1/500. Western blot. Functional assay: Neutralises the bioactivity of IL-1 beta. Removal of Sodium Azide is recommended prior to use.
Reactivity	Sheep
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant IL-1 beta
Specificity	This antibody recognizes Interleukin-1 beta (IL-1 beta). No cross-reactivity is seen with ovine IL-6, IL-8, MCP-1 or TNF alpha.
Formulation	0.09% Sodium Azide State: Serum State: Liquid serum
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID P21621
Background	Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
Synonyms	IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin
Reference Data

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