TAP1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FC, IP, WB
Recommend Dilution	Flow Cytometry. ELISA: 1/10,000. Immunoprecipitation. Western Blot: 1/1000. Detects a band of approximately 72kDa.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	TAP1 peptide corresponding to the C-terminal of the human protein conjugated to KLH.
Specificity	This antibody detects an epitope within the C-terminal region of Human TAP1, also known as transporter associated with antigen processing 1. This antibody does not cross react with TAP2.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.01% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Database Link	Entrez Gene 6890 Human UniProt ID Q03518
Background	TAP1 is an 81kD membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.
Synonyms	PSF1, RING4, Y3
Reference Data

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