LNX1 Rabbit Polyclonal Antibody
CAT#: AP05289SU-N
LNX1 rabbit polyclonal antibody, Purified
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CNY 5,937.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: (1-5 µg/ml). |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from the human LNX1 protein |
Specificity | This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain. |
Formulation | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. |
Gene Name | ligand of numb-protein X 1 |
Database Link | |
Background | LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 |
Synonyms | LNX, LNX-1, E3 ubiquitin-protein ligase LNX, Numb-binding protein 1, Ligand of Numb-protein X 1 |
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