BAPTA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IP, WB
Recommend Dilution	Western Blot: 1 - 10 µg/ml. Immunofluorescence. Immunoprecipitation.
Reactivity	Chicken, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody reacts to BAPTA.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Background	BAPTA (bis(o-aminophenoxy)-ethane-N,N,N’,N’-tetraacetic acid)is a calcium channel chelator. BAPTA has spawned many of the most familiar fluorescent indicators for calcium and other ions (1).BAPTA and its analogs including BAPTA-AM have proved most critical in cell physiology where they have been essential in defining the mechanisms underlying intra or intercellular calcium homeostasis (2).and calcium dependant exocytosis (3).BAPTA and its analogs may also find application in diseases which a disturbed regulation of excitatory neurotransmitter release and uptake plays a role (4). The rabbit BAPTA antibody recognizes a 69 kDa monomer and 138 kDa dimer by western blot. The immunogen used was a recombinant BAPTA-KLH.
Reference Data

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