Comp Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot (1:1000).
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant rat COMP (Type III repeats + C-terminal region)
Specificity	This antibody detects COMP.
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Gene Name	cartilage oligomeric matrix protein
Database Link	Entrez Gene 25304 Rat UniProt ID P35444
Background	COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Synonyms	Cartilage oligomeric matrix protein
Note	LocusID 25304
Reference Data

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