BNP (NPPB) (NT-proBNP 32-57) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, R
Recommend Dilution	RIA. ELISA (as Capture antibody in Sandwich ELISA).
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic Human pro-BNP (aa 32-57).
Specificity	This antibody detects synthetic Human pro-BNP (aa 32-57). There were no cross reactivities obtained with Human pro-BNP (aa 8-29).
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	natriuretic peptide B
Database Link	Entrez Gene 4879 Human UniProt ID P16860
Background	In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
Synonyms	NPPB, Brain natriuretic peptide, BNP, proBNP
Note	Reference no.: LocusID 4878
Reference Data

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