Pneumadin / PNM Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic human Pneumadin, poly Lysin conjugated
Specificity	This antibody detects synthetic Pneumadin.
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Database Link	UniProt ID P22103
Background	Normal mammalian lungs, including human fetal lungs, contain significant amounts of a decapeptide which releases arginine-vasopressin from the neurohypophysis and therefore has antidiuretic activity. The rat peptide is: Tyr-Gly-Glu-Pro-Lys-Leu-Asp-Ala-Gly-Val-NH2. The peptide from human fetal lungs has Ala instead of Tyr. It may be a normal regulatory substance and its role in the pathogenesis of the syndrome of inappropriate antidiuresis associated with lung diseases merits investigation.
Reference Data

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