Natriuretic Peptide Receptor A (NPR1) (294-308) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 1/1000-1/5000. Immunocytochemistry (Ref.2). Immunohistochemistry on Paraffin Sections: 1/4000 (Ref.1).
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Human NPR-A (aa 294-308) KLH conjugated
Specificity	This antibody detects Synthetic Human NPR-A (aa 294-308) and cross reactivity with Rat NPR-A
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	natriuretic peptide receptor 1
Database Link	Entrez Gene 4881 Human UniProt ID P16066
Background	Natriuretic peptide receptor A is a receptor for atrial natriuretic peptide, and has guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity(ANP-A and ANP-B) and one (ANP-C) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. ANP-A Belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.
Synonyms	ANP receptor A, ANP-A, NPR-A, Guanylate cyclase, GC-A, Atrial natriuretic peptide A-type receptor
Note	LocusID 4881
Reference Data

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