Myeloperoxidase (MPO) Rabbit Polyclonal Antibody
CAT#: AP02121SU-N
Myeloperoxidase (MPO) rabbit polyclonal antibody, Serum
Size: 10 ug
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CNY 3,490.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | ELISA, IHC |
Recommend Dilution | ELISA. Immunohistochemistry on Paraffin Sections. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Human Myeloperoxidase |
Specificity | This antibody detects Myeloperoxidase (MPO). |
Formulation | TRIS, pH 7.4 State: Serum State: Lyophilized purified Serum |
Reconstitution Method | Restore in aqua bidest to 1 mg/ml. |
Purification | Protein G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | myeloperoxidase |
Database Link | |
Background | Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers. |
Synonyms | MPO |
Reference Data |
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