Laminin 5 (LAMB3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot (Ref.1,2,5,7) Immunoprecipitation (Ref.3) Immunocytochemistry (Ref.5,7) Immunohistochemistry on Cryosections (Ref.3,4,6,7).
Reactivity	Human, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human Laminin 5.  Laminin 5 consists of three chains: Alpha-3, Beta-3 and Gamma-2
Specificity	This antibody detects Human and bovine total Laminin 5.
Formulation	PBS State: Purified State: Lyophilized purified IgG fraction from Serum.
Reconstitution Method	Restore in 100µl aqua bidest
Purification	Protein G Chromatography.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C. Avoid repeated freezing and thawing.
Gene Name	laminin subunit beta 3
Database Link	Entrez Gene 3914 Human UniProt ID Q13751
Background	Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	LAMB3, LAMNB1, Laminin subunit beta-3, Laminin 5, Laminin B1k chain, Kalinin B1 chain
Note	LocusID 3911
Reference Data

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