Calcitonin (CALCA) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	R
Recommend Dilution	RIA (1/80,000).
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	Synthetic Human Calcitonin, BSA-conjugated
Specificity	This antibody detects Calcitonon. There were no cross reactivities obtained with Human Katacalcin and Human Calcitonin Gene related Peptide.
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
Synonyms	CALCA, CALC1
Note	LocusID 796
Reference Data

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