FGF2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, R, WB
Recommend Dilution	RIA (Ref.1,2). Western blot: 1/10,000-1/30,000 (Ref.1,2). Immunohistochemistry on Frozen Sections: 1/5,000 (Ref.1-3). Immunohistochemistry on Paraffin Sections: 1/200 (Ref.1-3).
Reactivity	Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Bovine Fibroblast Growth Factor-2 [FGF-2] (= basic FGF)
Specificity	This antibody detects Fibroblast Growth Factor-2. Does not cross react with FGF-1, IGF-1, IGF-2, TNFa and EGF.
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	fibroblast growth factor 2
Database Link	UniProt ID P09038
Background	FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Synonyms	FGFB, Heparin-binding growth factor 2, Fibroblast growth factor 2 (basic), BFGF, HBGF-2, HBGF2
Reference Data

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