GPR103 (QRFPR) Rabbit Polyclonal Antibody

CAT#: AP01429PU-N

GPR103 (QRFPR) rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



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CNY 1,999.00

CNY 4,640.00


货期*
2周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications ELISA, IF, WB
Recommend Dilution Western Blot: 1/500 - 1/1000.
Immunofluorescence: 1/50-1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Specificity GPR103 antibody detects endogenous levels of GPR 103 protein. (region surrounding Ile310)
Formulation Phosphate buffered saline (PBS), pH~7.2 with 0.05% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 49 kDa
Gene Name pyroglutamylated RFamide peptide receptor
Background G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455 amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.
Synonyms Orexigenic neuropeptide QRFP receptor, G-protein coupled receptor 103, SP9155, AQ27
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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