MARCKS Rabbit Polyclonal Antibody

CAT#: AP01344PU-N

MARCKS rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



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CNY 1,999.00

CNY 4,640.00


货期*
2周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications WB
Recommend Dilution Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Specificity MARCKS antibody detects endogenous levels of MARCKS protein. (region surrounding Lys152)
Formulation Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 45 kDa
Gene Name myristoylated alanine rich protein kinase C substrate
Background Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC α and PKC ε, but not PKC δ, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.
Synonyms Myristoylated alanine-rich C-kinase substrate, MACS, PRKCSL
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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