NMBR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 235-280 of Human NMBR.
Specificity	This antibody detects endogenous levels of Neuromedin B receptor / NMBR protein (region surrounding Leu264).
Formulation	Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium azide
Concentration	1.0 mg/ml
Purification	Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 43 kDa
Gene Name	neuromedin B receptor
Database Link	Entrez Gene 4829 Human UniProt ID P28336
Background	The bombesin receptor family includes the gastrin-releasing peptide (GRPR) and neuromedin B (NMBR) receptors. Both receptors are expressed in various brain regions and in the digestive tract. NMBR belongs to the G proteincoupled receptor 1 family. The gene encoding NMBR protein maps to chromosome 6q21-qter. NMBR, an integral membrane protein, binds neuromedin B, a mitogen and growth factor for gastrointestinal epithelial tissue and normal and neoplastic lung.
Synonyms	NMB-R, NMBR
Reference Data

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