PDE4 (PDE4B) Rabbit Polyclonal Antibody

CAT#: AP00656SU-N

PDE4 (PDE4B) rabbit polyclonal antibody, Serum



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CNY 5,950.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, IP, WB
Recommend Dilution Western blot (1:20000).
Immunohistochemistry.
Immunoprecipitation.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Designed from the C-terminal region common to all 4B isoforms
Specificity The antibody selectively detects proteins corresponding to members of the PDE4B sub-family.
Formulation State: Serum
State: Liquid diluted serum
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name phosphodiesterase 4B
Background Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'-
monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP.
Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.
Synonyms PDE4B, DPDE4, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, EC=3.1.4.17, PDE32
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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