PDE3A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Western blot (see picture below). Immunohistochemistry. Immunoprecipitation.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Designed from the C-terminal region common to the 3A isoform.
Specificity	The antibody selectively detects proteins corresponding to PDE3A.
Formulation	State: Serum State: Liquid diluted serum
Conjugation	Unconjugated
Storage Condition	Store the antiserum at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphodiesterase 3A
Database Link	Entrez Gene 5139 Human UniProt ID Q14432
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE3 enzyme belongs to a family of PDEs known as cGMP-inhibited PDEs. The enzymes bind both cGMP and cAMP with different affinities. The PDE3 family is comprised of two genes, PDE3A and PDE3B.
Synonyms	Phosphodiesterase 3A, Phosphodiesterase-3A cGMP-inhibited, CGI-PDE, CGI-PDE A
Reference Data

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