Nlgn3 (730-848, Intracell. Dom.) Mouse Monoclonal Antibody [Clone ID: S110-29]

Specifications

Product Data
Clone Name	S110-29
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 1/1000; 1 μg/ml was sufficient for detection of Neuroligin-3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using HRP conjugated secondary antibody. Immunocytochemistry. Immunohistochemistry: Free floating sections, fixed in formaldehyde.
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 730-848 (intracellular, C-terminus) of rat Neuroligin 3.
Specificity	This antibody detects Neuroligin 3; ~110 kDa. Does not cross-react with Neuroligin-1, -2 or -4.
Formulation	PBS pH 7.4, 50% Glycerol, 0.09% Sodium azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Protein G chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	neuroligin 3
Database Link	Entrez Gene 171297 Rat UniProt ID Q62889
Background	Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
Synonyms	NLGN3, KIAA1480, NL3
Reference Data

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