LDHB Mouse Monoclonal Antibody [Clone ID: AT14D7]

Specifications

Product Data
Clone Name	AT14D7
Applications	ELISA, WB
Recommend Dilution	The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human LDHB (1-334aa) purified from E. coli.
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lactate dehydrogenase B
Database Link	Entrez Gene 3945 Human UniProt ID P07195
Background	LDHB, also known as L-lactate dehydrogese B chain, is a member of the lactate dehydrogese family. It is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of DH and D+. As this protein can also catalyze the oxidation of hydroxybutyrate, it is occasiolly called Hydroxybutyrate Dehydrogese (HBD). The LDH family consists of three members, LDH-A, LDH-B and LDH-C. LDHs function as powerful markers for germ cell tumors.
Synonyms	LDHB, L-lactate dehydrogenase B chain, LDH-B, EC=1.1.1.27, LDH heart subunit, LDH-H, Renal carcinoma antigen NY-REN-46
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism

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