RAIDD (CRADD) Mouse Monoclonal Antibody [Clone ID: AT14G8]

CAT#: AM50351PU-S

RAIDD (CRADD) mouse monoclonal antibody, clone AT14G8, Purified



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CNY 5,630.00


货期*
5周

规格
    • 50 ul

Product images

Specifications

Product Data
Clone Name AT14G8
Applications ELISA, WB
Recommend Dilution This antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.
Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Recommended Starting Dilution: 1/500.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human CRADD (1-199aa) purified from E. coli.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CASP2 and RIPK1 domain containing adaptor with death domain
Background CRADD, also referred as RAIDD, is an adaptor protein that could interact with both caspase 2 and RIP that can promote apoptosis once activated. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.
Synonyms CRADD
Reference Data
Protein Families Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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