VEGF Receptor 2 (KDR) Mouse Monoclonal Antibody [Clone ID: KDR721]
CAT#: AM50324PU-T
VEGF Receptor 2 (KDR) mouse monoclonal antibody, clone KDR721, Purified
Size: 100 ug
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CNY 3,223.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | KDR721 |
Applications | FC, IF, IHC, IP |
Recommend Dilution | ELISA: Use BSA free Antibody for coating. Flow Cytometry: 0.5-1 µg/million cells. Immunofluorescence: 0.5-1 µg/ml. Functional Studies: Use BSA and Azide Antibody. Immunoprecipitation: 0.5-1 µg/ 500 µg protein lysate. Immunohistochemistry on Frozen Sections: 0.5-1.0 µg/ml for 30 minutes at RT. Positive Control: HUVEC cells, Human lymph nodes and tonsils. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant Human VEGF-R2 protein. |
Specificity | Recignizes Human VEGF-R2 / CD309 / Flk-1 / KDR3. Other species not tested. Cellular Localization: Cell surface. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 150-230 kDa |
Gene Name | kinase insert domain receptor |
Database Link | |
Background | CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration. |
Synonyms | VEGFR2, FLK1, KDR, VEGF Receptor 2 |
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